@article{oai:jissen.repo.nii.ac.jp:00002078,
 author = {青木, 敦子 and 秋田, 修 and 松岡, 康浩 and 冨重, 慶子 and 松島, 照彦},
 journal = {実践女子大学生活科学部紀要, Bulletin of Jissen Women's University Faculty of Human Life Sciences},
 month = {Mar},
 note = {Using ultraviolet-irradiated mouse fibroblasts as a model for cell damage, we analyzed collagen synthesis and secretion into the culture medium and changes in gene expression of proteins involved in collagen synthesis and metabolism. Various food ingredients and nutritional elements were added to the culture medium and their effects were analyzed. Secretion and accumulation of collagen was decreased depending on the duration of ultraviolet-irradiation. The addition of collagen peptides increased the secretion of collagen into the medium. Following the addition of resveratrol, the main functional polyphenol of red wine, membrane-bound collagen was decreased, collagen secretion into the medium was increased, and gene expression of collagen-I, collagen-II, and collagenase was increased. We, therefore, suggest that collagen metabolism may be activated by resveratrol.},
 pages = {23--30},
 title = {コラーゲン産生に対して食品の機能性成分が与える影響  ～ 紫外線照射線維芽細胞を細胞傷害モデルとした 細胞生物学的解析 ～},
 volume = {56},
 year = {2019}
}