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乳酸菌が脂質代謝に与える影響についての 培養腸管細胞Caco2を用いた検討
https://doi.org/10.34388/1157.00001416
https://doi.org/10.34388/1157.00001416073a2a56-029d-4ac0-ba25-982044089489
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
生活科学53-2 (780.4 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-05-21 | |||||
| タイトル | ||||||
| タイトル | 乳酸菌が脂質代謝に与える影響についての 培養腸管細胞Caco2を用いた検討 | |||||
| タイトル | ||||||
| タイトル | The effect of Lactobacillus acidophilus strain L-55 on chylomicron apoB48 synthesis and secretion by cultured intestinal cells | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 乳酸菌L-55株 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | カイロミクロン | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | アポ蛋白B48 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ヒト大腸癌細胞由来Caco-2細胞 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Lactobacillus acidophilus Strain L-55 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | chylomicron | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | apoB48 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Caco-2 | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ID登録 | ||||||
| ID登録 | 10.34388/1157.00001416 | |||||
| ID登録タイプ | JaLC | |||||
| 著者 |
冨重, 慶子
× 冨重, 慶子× 松島, 照彦 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 3154 | |||||
| 姓名 | Tomishige, Keiko | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 3155 | |||||
| 姓名 | Matsushima, Teruhiko | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Postprandial hyperlipidemia has been noted as a risk factor in cardiovascular diseases and cell biological studies targeted on intestinal tract is important for the analysis of the secretion of chylomicron. Meanwhile, preventive potentials for atherosclerosis were reported in many functional foods and food components. In order to elucidate the effect of lactic acid bacteria on chylomicron metabolism, we investigated the secretion of apoliporotein B48 (apoB48) in cultured intestinal cells. Human intestinal cell line Caco-2 cells were cultured on the pored membrane of double-based dishes and Lactobacillus acidophilus strain L-55 was added with lipid micelles to the upper chamber. We established an anti-apoB-48 monoclonal antibody, and apoB-48 secreted into the medium was quantified by ELISA. By the addition of L-55, apoB48 secretion was significantly decreased as compared to the control. There was no difference in the decrease between living cells and the heat-killed cells. However, there was a difference in the amount secreted by the timing of the addition and the number of lactic acid bacterium. An observed reduction in the secretion of apo B48 is considered to indicate a decrease in the chylomicron particle numbers. It was suggested that Lactobacillus L-55 may be useful in the control prevention of arteriosclerosis. | |||||
| 書誌情報 |
実践女子大学生活科学部紀要 en : Bulletin of Jissen Women's University Faculty of Human Life Sciences 巻 53, p. 7-12, 発行日 2016-03-31 |
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| 出版者 | ||||||
| 出版者 | 実践女子大学 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13413244 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN10494731 | |||||
